日批在线视频_内射毛片内射国产夫妻_亚洲三级小视频_在线观看亚洲大片短视频_女性向h片资源在线观看_亚洲最大网

Global EditionASIA 中文雙語Fran?ais
World
Home / World / China-Europe

Mutation discovery could help prevent genetic disorders

By Angus McNeice in London | chinadaily.com.cn | Updated: 2018-01-11 01:58
Share
Share - WeChat

Scientists from Britain and China have made a discovery that might lead to the ability to repair mutations in genes that cause harmful disorders, such as cystic fibrosis and certain cancers.

Geneticists at the United Kingdom's Oxford University and Zhejiang University in China have discovered that cells rank genes by importance, and give certain regions of our genetic make-up special treatment when repairing mutations.

Genetic mutations are one of the driving forces of evolution. They happen when a cell makes an error while copying DNA – the molecules that make up our genes. Some mutations cause no harm or even end up being beneficial, but others are responsible for illnesses such as muscular dystrophy and types of cancer.

Nicholas Harberd, a plant geneticist at Oxford University and lead author of the study, said his research suggests cells have found a way to target "important" regions of genetic material for protection against mutation, and that they focus less attention on other regions.

The study, published in the journal Genome Research, looks at a mechanism called DNA mismatch repair, or MMR, in plant cells.

During the MMR process, which occurs in cells throughout the animal and plant kingdom, an enzyme repairs parts of DNA that have been copied incorrectly during cell replication.

The scientists compared the frequency and distribution of mutations in the genome of plants that were proficient in MMR against those in a plant strain that was not able to perform MMR.

The genome is the sum of the genetic material in a cell. A minority of an organism's genome is made up of genes which code for proteins – large regions of the genome are made up of "non-coding" DNA.

The researchers found that in the MMR-deficient strain, mutations were more regular and were randomly distributed throughout the genome.

In the MMR-proficient plant genome, mutations were less regular and were not as randomly distributed. Areas of the genome that code for genes had fewer mutations than areas of the genome that do not code for genes.

"It suggests that our cells and the cells of living organisms have developed the ability to target their protection particularly to genes, rather than non-gene parts of the genome," Harberd said.

Harberd said the discovery could provide valuable information to scientists who are developing ways to eliminate harmful mutations in the human genome. Other gene editing processes found in nature – such as CRISPR – have led to technology that can alter the genome with incredible accuracy.

"From a scientific perspective, that's probably quite reasonable," Harberd said. "But that's very much in the long term, and that whole issue is fraught with ethical and legislative concerns. What's exciting is that we've come to understand more about evolution and variation. Mutation is often described as being a random process – I guess what we are suggesting is that it's somewhat less random that previously people had realized."

Most Viewed in 24 Hours
Top
BACK TO THE TOP
English
Copyright 1994 - . All rights reserved. The content (including but not limited to text, photo, multimedia information, etc) published in this site belongs to China Daily Information Co (CDIC). Without written authorization from CDIC, such content shall not be republished or used in any form. Note: Browsers with 1024*768 or higher resolution are suggested for this site.
License for publishing multimedia online 0108263

Registration Number: 130349
FOLLOW US
主站蜘蛛池模板: 欧美视频中文字幕 | 中文字幕在线永久 | 亚洲自拍小说 | 日本韩国欧美在线 | 成人亚洲网 | 在线观看日本网站 | 日韩在线资源 | 亚洲欧美第一 | 国产无遮挡免费视频 | 青青成人网 | 色狠狠综合| 天天看天天摸天天操 | 大乳av| 日韩最新在线 | 成人丁香婷婷 | 欧美黄色性视频 | 男人操女人的视频网站 | 九九热av | 成人夜间视频 | 色导航在线| 成人亚洲在线 | 日日噜噜噜夜夜爽爽狠狠 | 国产三级精品视频 | 国产精品久久久久无码av | 日韩精品亚洲精品 | 精品国产99久久久久久 | 免费看黄网站在线观看 | 久久精品av | 欧美日韩精品在线视频 | 欧美日本一区二区 | 毛片网站有哪些 | 国产精视频 | 午夜不卡av | 中文字幕黄色 | 男人的天堂中文字幕 | 久久免费一区 | 成人高清视频在线观看 | 青青草原伊人网 | 精品玖玖玖 | 午夜视频黄 | 亚洲免费资源 |