Milwaukee superstar Giannis Antetokounmpo and Memphis star guard Ja Morant suffered injuries that threatened to disrupt two title contenders on Sunday in NBA playoff series-opening defeats.

The Los Angeles Lakers took advantage of Morant's absence late in the fourth quarter for a late surge that produced a 128-112 victory at Memphis while the top-seeded host Bucks, who lost their Greek star in the first quarter, fell 130-117 to the eighth-seeded Miami Heat.

But injury fears for Antetokounmpo and Morant, two of the NBA's most electrifying stars, were amplified by upset home losses for their clubs in best-of-seven first-round openers.

Antetokounmpo has averaged 31.1 points and 11.8 rebounds this season for an NBA-best 58-24 Bucks squad while Morant averaged 26.2 points for a Grizzlies team that was 51-31.

Morant hurt his already-sore right hand midway through the fourth quarter trying to brace a hard landing to a high fall after contact while driving to the basket.

Morant's taped right hand took the impact. Morant rose and ran off to the locker room, grabbing his sore hand and screaming as he exited after scoring 18 points.

"I'm in a good bit of pain," Morant said, declaring his status was "in jeopardy" for Game 2 on Wednesday. "Feels like it's one thing after another," he added.

Memphis coach Taylor Jenkins said after the game that X-rays on Morant's right hand were negative but he would likely be kept out of workouts and his status is "one game at a time".

At Milwaukee, Antetokounmpo went onto the floor in the first quarter after defensive contact on a move to the hoop and suffered a lower back bruise that ended his night with Game 2 in Milwaukee on Wednesday.

"We'll monitor him," said Bucks coach Mike Budenholzer, who added an X-ray came back "clear" on Antetokounmpo.

"We have to wait and see what the doctors say... you've got to take it day by day and see how he's doing and how he feels."

The Heat, among the NBA's worst 3-point shooting teams this season, made 15-of-25 from beyond the arc at Milwaukee.

While the Bucks had gone 11-8 in games without Antetokounmpo this season, the Heat led by as many as 15 points with the big man gone.

Miami suffered its own injury setback when guard Tyler Herro suffered a broken right hand diving for a loose ball in the final seconds of the second quarter. He's expected to be out four to six weeks after averaging 20.1 points this season.

Jimmy Butler led Miami with 35 points and 11 assists. Gabe Vincent was 4-of-5 from 3-point range and Kevin Love was 4-of-7 on 3-pointers.

With Antetokounmpo scoring only eight points, Khris Middleton led the Bucks with 33 points.

Clippers eclipse Suns

Kawhi Leonard scored 13 of his game-high 38 points in the fourth quarter to spark the Los Angeles Clippers to a 115-110 victory at Phoenix in their series opener.

Russell Westbrook had nine points, 10 rebounds, eight assists and three blocked shots, the biggest on Devin Booker in the final seconds to help seal victory.

Kevin Durant had 27 points, 11 assists and nine rebounds but suffered his first loss in the nine games he has played since joining the Suns from Brooklyn.

Clippers forward Paul George was out with a sprained right knee and is questionable for the playoffs.

AFP