LOS ANGELES — Floyd Mayweather and Manny Pacquiao will meet in a long-awaited rematch of the highest-grossing clash in boxing history this September at Sphere in Las Vegas, Netflix announced Monday.

News of the bout between two of boxing's biggest names — who famously fought a blockbuster clash in 2015, and are now both in their late forties — comes days after Mayweather announced he is coming out of retirement.

It will be broadcast live on Sept 19 on Netflix, as the global streaming platform increasingly moves into live sports with glitzy one-off events.

"Floyd and I gave the world what remains the biggest fight in boxing history. The fans have waited long enough — they deserve this rematch," said Pacquiao, 47, in a joint statement.

Mayweather beat fellow welterweight Pacquiao in their money-spinning 2015 "Fight of the Century", which generated a record 4.6 million pay-per-view purchases, but largely failed to live up to the hype.

Mayweather is believed to have earned an estimated $300 million from the unanimous points victory over the Filipino icon, which remains the most lucrative fight in history and generated more than $600 million in revenue.

Former multi-weight world champion Mayweather retired from boxing in 2017, unbeaten in 50 bouts, though he has continued to fight in exhibitions since, including an upcoming clash this spring with Mike Tyson.

Pacquiao, also a multiple world champion, retired for a four-year period from 2021 in which he unsuccessfully ran for the Philippine presidency. He came out of retirement last year.

Rumors of a Mayweather-Pacquiao rematch have circulated for years, and speculation soared following Mayweather's announcement last week that he would return to the professional arena this year.

"I already fought and beat Manny once. This time will be the same result," said Mayweather, in the statement.

"I want Floyd to live with the one loss on his professional record, and to always remember who gave it to him," said Pacquiao.

The clash will be the first-ever professional boxing match to take place at Sphere, a venue primarily used for concerts and films that opened in 2023 and features an immersive 160,000-square-foot wraparound screen on its curved interior walls.

It will be shown globally on Netflix, which boasts some 325 million subscribers.

The streaming service has recently increased its sports offerings, with a super middleweight clash between Terence Crawford and Saul "Canelo" Alvarez in Las Vegas last September viewed by 41 million people.

It also aired divisive fights pitting YouTuber-turned-boxer Jake Paul against a 58-year-old Tyson in November 2024, and versus Anthony Joshua last December.

Both were criticized for proving to be lackluster contests, but drew enormous global attention.

Nicknamed "Money", former multi-weight world champion Mayweather was once the world's highest-paid athlete. His last professional bout took place in 2017 against UFC star Conor McGregor.

The 48-year-old American has long been a controversial figure, often criticized for an overly defensive style, and accused by some of dodging the most dangerous opponents simply to embellish his record.

Mayweather has also spent time in prison for one of a string of domestic violence incidents.

Pacquiao known at home as "The National Fist" and more broadly as "Pac-Man", is an eight-division world champion.

He is beloved in the Philippines for his rags-to-riches story, having dropped out of high school at 14, selling donuts on the roadside and working as a grocery store shelf stacker.

Pacquiao, having already served as a Philippines senator since 2016, retired for a four-year period from 2021, during which he attempted to win the country's top political office.

The diminutive southpaw came out of retirement last year. He was held to a draw by Mario Barrios, putting his professional record at 62-8-3.

"As always, I dedicate this fight to my fellow Filipinos around the world, and to bringing glory to the Philippines," said Pacquiao.