WASHINGTON DC: The first practical proposals to reduce the number of nuclear weapons are expected to be central to a second summit between the leaders of the world's two most powerful nations.

US President Barack Obama and his Russian counterpart Dmitry Medvedev will hold meetings in Moscow from Sunday until Tuesday following what the Obama administration described as a desire to "push the re-set button" on relations with Russia.

The two called for the eventual total elimination of nuclear weapons during their first meeting in London in April. Together, the two countries possess 95 percent of the world's nuclear arsenal.