One of China's largest tour operators has suspended cooperation with Malaysia Airlines and said it will cancel existing flight arrangements with the carrier.

"Considering the fact that a succession of accidents have involved Malaysia Airlines recently, and that Chinese tourists have concerns over the carrier's safety record, we must fulfill our responsibility of ensuring the security of our fellow citizens," Beijing-based China Youth Travel Service said in a statement on Wednesday.

New bookings will be suspended and existing itineraries that include Malaysia Airlines will be changed to other carriers, it said.