日批在线视频_内射毛片内射国产夫妻_亚洲三级小视频_在线观看亚洲大片短视频_女性向h片资源在线观看_亚洲最大网

USEUROPEAFRICAASIA 中文雙語Fran?ais
Lifestyle
Home / Lifestyle / Health

Chinese scientists identify way, drugs for nerve damage treatment

Xinhua | Updated: 2017-08-03 10:15

Research led by Chinese scientists may lead to a potential new therapy for the currently untreatable delayed neuropathy caused by acute exposure to insecticides or chemical weapons that attack the nervous system, a study published Tuesday in the journal Cell Discovery revealed.

A research team identified a new biological mechanism responsible for the neuropathy, as well as the drugs to treat it.

Organophosphates (OP), the chemical compound found in insecticides, herbicides, and nerve agents such as sarin, were found to damage sensory neurons by activating a channel, called TRPA1, in the neuron cell membrane.
Activation of TRPA1 caused hyper-activation of the neuron, which is known to cause neuronal damage and symptoms including burning pains on the skin, loss of muscle control and paralysis.

Mice that were genetically engineered not to express TRPA1 in neuronal cells did not suffer the effects of OP poisoning that were seen in normal mice and their nerves showed no signs of damage, according to the study.

This study provides compelling evidence that TRPA1 mediates OP-induced neuropathy and that TRPA1 can be targeted effectively with existing drugs that are approved by the Federal Drugs Administration, said the study's lead author

Dr. Gao Zhaobing, from the Shanghai Institute of Materia Medica, Chinese Academy of Sciences.

"Using our expertise in drug discovery we were also able to screen a Federal Drugs Administration-approved drug library of around 2,000 drugs and identify two potent drugs, duloxetine and ketotifen, which alleviated the signs of neuropathy in an animal model," said Gao.

Further research is needed to assess whether the findings are applicable to humans, according to the authors.

Copyright 1995 - . All rights reserved. The content (including but not limited to text, photo, multimedia information, etc) published in this site belongs to China Daily Information Co (CDIC). Without written authorization from CDIC, such content shall not be republished or used in any form. Note: Browsers with 1024*768 or higher resolution are suggested for this site.
License for publishing multimedia online 0108263

Registration Number: 130349
FOLLOW US
主站蜘蛛池模板: 国产精品久久久久久久久久久久 | 精品在线观看视频 | 欧美亚洲在线视频 | 夜夜爽av福利精品导航 | 美女黄页在线观看 | 91视频最新 | 成人四虎影院 | 在线观看的av网站 | 亚洲黄色免费看 | 天天射一射| 欧美另类精品 | 一区二区三区国产在线 | 51成人做爰www免费看网站 | 日韩av免费在线看 | 超碰日本| 欧美一级在线播放 | 久草在在线 | 免费无遮挡在线观看视频网站 | 狠狠五月 | 午夜aaaa | 日本天堂网在线观看 | 国产极品在线播放 | 一区二区三区福利视频 | 成年人免费av | 国产精品久久久久久久久久久久久久 | 久久久久久久久久久影院 | 成人免费视频网 | 亚洲欧美日韩免费 | 艹男人的日日夜夜 | 青青操在线视频 | 欧美精品在线免费观看 | 欧美一a一片一级一片 | 伊人网在线播放 | 国产午夜网站 | 日批免费观看 | 国偷自拍第113页 | 91精品看片 | av在线天堂| 成人国产精品视频 | 午夜一级大片 | 日韩精品国产精品 |