The city of S-hertogenbosch, the Netherlands, established a sister city relationship with Wuxi on February 10, 2010.

As the capital of North Brabant province, it is one of the areas with high-developed technology and services in the Netherlands, and is the arts and commercial center of middle Netherlands.

In 2008, S-hertogenbosch was honored as the strongest economic strength city in the Netherlands by Elsevier, an authoritative magazine in the county. It is also the home of many celebrated enterprises, banks, accounting firms and consulting corporations, such as SAP, Acer, Heineken, KPN and Omron.