Turkish President Tayyip Erdogan makes a speech during a meeting in Ankara, Turkey February 17, 2016, in this handout photo provided by the Presidential Palace. [Photo/Agencies]

ANKARA - Twenty-eight people were killed and dozens wounded in Turkey's capital Ankara on Wednesday when a car laden with explosives detonated next to military buses near the armed forces' headquarters, parliament and other government buildings.

The Turkish military condemned what it described as a terrorist attack on the buses as they waited at traffic lights in the administrative heart of the NATO member's capital.

The attack, the latest in a series of bombings in the past year mostly blamed on Islamic State, comes as Turkey gets dragged ever deeper into the war in neighbouring Syria and tries to contain some of the fiercest violence in decades in its predominantly Kurdish southeast.

President Tayyip Erdogan said Turkey's determination to fight those behind such acts would only get stronger and that it would not hesitate to exercise its right to self defence.

"We will continue our fight against the pawns that carry out such attacks, which know no moral or humanitarian bounds, and the forces behind them with more determination every day," he said in a written statement.

Deputy Prime Minister and government spokesman Numan Kurtulmus said 28 people including soldiers and civilians were killed and 61 wounded in the blast, which occurred near a busy intersection less than 500 metres from parliament during the evening rush hour.

Justice Minister Bekir Bozdag described the attack as an act of terrorism and told parliament, which was in session at the time, that the car had exploded on a part of the street lined on both sides by military vehicles.